Protein aim2

Author: ibzd

August undefined, 2024

WebJan 22, 2011 · Absent in melanoma 2 (AIM2) is an essential cytosolic double-stranded DNA receptor that assembles with the adaptor, … WebSep 14, 2024 · Absent in melanoma 2 (AIM2) is originally identified as a tumor suppressor of melanoma and named absent in melanoma 2. 1 AIM2 is a member of the interferon (IFN) …

6MB2: Cryo-EM structure of the PYD filament of AIM2 - RCSB

WebHuman Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome . Persistent infection with HCMV is associated with the operation of diverse evasion phenotypes directed at antiviral immunity. WebNov 11, 2016 · Hu et al. found a pathological role for the protein AIM2 in irradiation-induced tissue damage. AIM2 is best known for its role in sensing double-stranded DNA in the … ge fuf21qrrww review

Inflammasomes (SAB target list) Pathway Map - PrimePCR Life …

Web66902-1-Ig targets AIM2 in WB, IF, CoIP, ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples. PBS with 0.02% sodium azide and 50% glycerol pH … WebApr 11, 2024 · Our transcriptomic analysis, RT-qPCR, Western blot, immunofluorescence and flow cytometry studies consistently showed AIM2 gene up-regulation and protein … WebPYHIN proteins AIM2 and IFI204 sense pathogen DNA, while other PYHINs have been shown to regulate host gene expression through as-yet unclear mechanisms. We … gefu cookie press attachment

Holdings: Human Cytomegalovirus Immediate Early 86-kDa Protein …

The protein kinase PKR is critical for LPS− induced iNOS …

WebC-reactive protein polymorphisms and DNA methylation of the AIM2 gene influence associations between trauma exposure, posttraumatic stress disorder, and C-reactive … WebWe also evaluated the gene and protein expression of Aim2, caspase-1, proIl1β and proIl18 in the small intestine (ileum) of STZ-injected mice. At day 7 after STZ induction, we found … dcsaa volleyball playoffsWebChimeric antigen receptor T (CAR-T) cells, which are genetically engineered to express specific synthetic antigen receptors, can specifically target antigens and kill tumor cells. CAR-T cells are capable of specifically recognizing their target antigen through the single-chain fragment variable (scFv) binding domain, resulting in T cell activation in a major … dcsa centralized investigations

"WebJul 26, 2016 · For example, the cytosolic release of microbial double-stranded DNA is detected by the C-terminal DNA-binding region of the protein AIM2. This leads to AIM2 … " - Protein aim2

Protein aim2

AIM2 Protein Overview: Sequence, Structure, Function …

WebSep 1, 2024 · AIM2 responds to infection with herpes simplex virus 1 or Francisella novicida by driving assembly of a large multi-protein complex containing multiple inflammasome … WebThe Human Disease Blood Atlas contains information on the protein levels in blood in patients with different diseases, as well as, the panels of proteins associated with the …

Did you know?

WebAug 29, 2024 · Cryo-EM structure of the PYD filament of AIM2. Absent in melanoma 2 (AIM2) is an essential cytosolic double-stranded DNA receptor that assembles with the … WebMay 20, 2008 · PTHR12200:SF17 INTERFERON-INDUCIBLE PROTEIN AIM2 1 hit; PTHR12200 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER 1 hit; …

WebApr 10, 2024 · IC 100 is a novel humanized IgG4 monoclonal antibody that inhibits the inflammasome adaptor protein ASC. IC 100 attenuates both initiation and perpetuation of the inflammatory response. It does so by binding to a specific region of the ASC component of multiple types of inflammasomes, including (NLRP1, NLRP2, NLRP3, NLRC4, AIM2, … WebInteresting, these patients also showed an increased production of IL-1β in supernatants of PBMCs stimulated in vitro with the agonists of AIM2, NLRP1 and NLRC4 inflammasomes. Finally, the expression of caspase-1, NLRP1, IL-1β and IL-18 in GALT or peripheral blood was correlated with CD4+ T-cell count and viral load.

WebSurprisingly, HIN2 of p202 interacts with the AIM HIN domain. We propose that this results in a spatial separation of the AIM2 pyrin domains, and indeed p202 prevented the … WebThese genes, such as the inflammasome component Absent in Melanoma 2 (AIM2) and the Major Histocompatibility Complex, class I C (HLA-C) candidates, were mainly involved in the response of interferon to viral infection. We used the EWAS-identified sites to establish a DNA methylation signature ... Serum protein electrophoresis (SPE) ...

WebRIP3 protein is reported to be the key molecule to regulate cell apoptosis or cell necroptosis. If RIP3 expression is high, ... NLRP3, absent in melanoma 2 (AIM2), NLRC4 and Pyrin. The last four have been found to be involved in PANoptosis. NLRP3 activation and GSDMD-mediated pyroptosis play key roles in apoptosis and necroptosis.

WebAIM2 is a member of the hematopoietic nuclear PYHIN protein family [23]. AIM2 transcripts are expressed in non-lymphoid and lymphoid tissues [189]. It is the only human PYHIN … ge fuf14smrww upright freezerWebInterferon-inducible protein AIM2; Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome … gefu flower plush pillowWebJun 9, 2024 · Yap1, also known as Yap, is a protein that acts as a transcription regulator by activating the transcription of genes involved in cell proliferation and inhibiting … gef tp ayronWebJan 22, 2011 · Absent in melanoma 2 (AIM2) is an essential cytosolic double-stranded DNA receptor that assembles with the adaptor, apoptosis-associated speck-like protein containing a caspase recruitment domain ... gefu flowerWebSep 29, 2024 · BackgroundThe absent in melanoma 2 (AIM2) inflammasome is a multi-protein platform that recognizes aberrant cytoplasmic double-stranded DNA(dsDNA) … gefu granit mörser crunchy 17cmWeb经典一抗-AIM2 Antibody. Datasheet. Alternative Names. PYHIN4; Interferon-inducible protein AIM2. Item Names. Absent In Melanoma 2. Research Area. Tumor immunity; UniProt. O14862. Mol.Wt. ... Antigen-specific affinity chromatography followed by Protein A affinity chromatography PK30249. 货号 ... ge fuf17dlrww canadaWebUsing mouse and human cells, Hornung et al. (2009) identified the PYHIN (pyrin and HIN domain-containing protein) family member AIM2 as a receptor for cytosolic DNA, which … dcsa appeals