site stats

Cd44-slc1a2 gene fusions in gastric cancer

WebDec 10, 2024 · CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple physiological processes, and aberrant expression and dysregulation of CD44 contribute to tumor initiation and progression. CD44 represents a common biomarker of … WebCD44-SLC1A2 silencing caused significant reductions in intracellular glutamate concentrations and sensitized SNU16 cells to cisplatin, a commonly used …

CD44-SLC1A2 gene fusions in gastric cancer. - Abstract - Europe …

WebAug 19, 2014 · CD44–SLC1A2 gene fusions in gastric cancer. Sci. Transl. Med. 3, 77ra30 (2011). Article CAS PubMed Google Scholar Lee, J. et al. Identification of ROS1 rearrangement in gastric adenocarcinoma. Webi ACKNOWLEDGEMENT I am extremely grateful and indebted to my supervisor Associate Professor Patrick Tan and my co-supervisor Dr. Celestial Yap for their advice and … laura britt height and weight https://pabartend.com

RhoGAP domain-containing fusions and - Nature

WebTao J., et al., CD44-SLC1A2 Gene Fusions in Gastric Cancer. Science Translational Medicine. 3(77):77ra30 (2011) Testimonials. I am impressed with the fast and friendly response from both the technical and administrative staff. The lead time to completion of sequencing is pleasantly short. [HiSeq WGS Sequencing] (Dr. Ng Sock Hoon, Research ... WebNov 13, 2024 · The results of the present study demonstrated that the FN1 gene was upregulated in gastric cancer tissues compared with that in normal tissues in eight cohorts, ... , Oh HK, Leong SH, Lim SS, Tan IB, Ooi CH, Wu J, et al: CD44-SLC1A2 gene fusions in gastric cancer. Sci Transl Med. 3:77ra302011. View Article: Google Scholar: … WebJun 1, 2011 · CD44-SLC1A2 silencing caused significant reductions in intracellular glutamate concentrations and sensitized SNU16 cells to cisplatin, a commonly used chemotherapeutic agent in gastric cancer. We ... laura brioschi height

Cancer: Gene fusion identified in gastric cancer - Nature

Category:CD44-SLC1A2 gene fusions in gastric cancer ScholarBank@NUS

Tags:Cd44-slc1a2 gene fusions in gastric cancer

Cd44-slc1a2 gene fusions in gastric cancer

Abstract PR1: Genomic discovery of CD44-SLC1A2 gene fusions in …

WebOct 25, 2024 · Despite a trend for the prevalence of gene fusions in young cancer patients, no studies have systematically investigated novel fusions in young patients with DGCs due to the relative rarity of early-onset gastric cancer, which is notable for its strong enrichment of diffuse histology. ... For example, CD44-SLC1A2 fusion is found in both gastric ... WebApr 1, 2011 · SLC1A2 undergoes a genomic breakpoint in its 5 0 region and forms a fusion gene with CD44 in gastric and colorectal cancers (Tao et al., 2011;Shinmura et al., …

Cd44-slc1a2 gene fusions in gastric cancer

Did you know?

WebCD44-SLC1A2 gene fusions in gastric cancer Jiong Tao, Nian Tao Deng, Kalpana Ramnarayanan, Baohua Huang, Hue Kian Oh, Siew Hong Leong, Seong Soo Lim, Iain … WebFeb 2, 2016 · CD44-SLC1A2 silencing also significantly reduced intracellular glutamate levels and sensitized SNU16 cells to cisplatin. Fusions of SLC1A2 to upstream CD44 …

WebExploring the best biological understanding of Solute Carrier 1A family in lung cancer Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. WebApr 25, 2013 · The structure of the known gastric cancer gene fusion CD44/SLC1A2 is depicted for comparison (right panel). An internal start codon within exon 2 of SLC1A2 is …

WebJan 10, 2015 · A CD44-SLC1A2 fusion has recently been discovered in a subset of primary gastric cancers, and an APIP-SLC1A2 fusion has been described in a colon cancer … WebApr 6, 2011 · In primary tumors, CD44-SLC1A2 gene fusions were detected in 1 to 2% of gastric cancers, but not in adjacent matched normal gastric tissues. When we …

WebApr 1, 2011 · In primary tumors, CD44-SLC1A2 gene fusions were detected in 1 to 2% of gastric cancers, but not in adjacent matched normal gastric tissues. When we …

WebTitle: CD44-SLC1A2 gene fusions in gastric cancer: Authors: Tao, J. Deng, N.T. Ramnarayanan, K. Huang, B. Oh, H.K. Leong, S.H. Lim, S.S. Tan, I.B. Ooi, C.H. justin ryan simpson wifeWebDec 13, 2014 · Importantly, several fusion genes, DUS4L–BCAP29 [ 19 ], CD44-SLC1A2 [ 20] have been reported in gastric cancer in western country. In our study, 3 chimeric transcripts were supported by the two detection methods (Table 4 ). Among them, CBX3-C15orf57 was detected in healthy human beings before [ 25 ]. laura brooks attorneyWebNov 18, 2013 · CD44-SLC1A2 gene fusions in gastric cancer. Sci Transl Med 2011; 3: 77ra30. Article Google Scholar Zhang Y, Gong M, Yuan H, Park HG, Frierson HF, Li H . … laura britt nbc bay areaWebThe results suggest that the expression of SLC1A2 fusion transcripts is related to a subset of primary CRCs and may contribute to the elucidation of the characteristics of S LC1A 2 fusion-positive CRCs in the future. A CD44-SLC1A2 fusion has recently been discovered in a subset of primary gastric cancers, and an APIP-SLC1A2 fusion has been … laura brookshire doWebCD44-SLC1A2 gene fusions in gastric cancer. - CORE Reader. We are not allowed to display external PDFs yet. You will be redirected to the full text document in the repository in a few seconds, if not click here. laura briggs photographyWebCD44-SLC1A2 silencing caused significant reductions in intracellular glutamate concentrations and sensitized SNU16 cells to cisplatin, a commonly used chemotherapeutic agent in gastric cancer. We conclude that fusion of the SLC1A2 gene coding region to CD44 regulatory elements likely causes SLC1A2 transcriptional dysregulation, because … laura brookshire pediatricianWebThe CD44-SLC1A2 fusion transcript was expressed in cancerous tissue but not in corresponding non-cancerous tissue, and the fusion occurred between exon 1 of CD44 … laura brindley seattle